children are thought to suffer milder forms of cognitive impairment due to alcohol exposure in the womb.īut what about light drinking, a champagne toast or an occasional glass of wine at dinner? Women–pregnant, pre-pregnant, and otherwise–receive conflicting advice about the safety of light drinking.Įconomist Emily Oster, in her bestselling pregnancy advice book Expecting Better, says pregnant women can be comfortable with “1 to 2 drinks a week in the first trimester” and one drink daily afterward, a stance she continues to stand behind. Fetal alcohol syndrome, caused by heavy drinking during pregnancy, affects an estimated 2 to 7 children out of 1000. We all know that heavy drinking and binge drinking are harmful during pregnancy. The (completely understandable) outrage at the CDC’s tone-deaf and condescending messaging has, unfortunately, drowned out information on the key question for many pregnant women: Is any amount of alcohol during pregnancy okay? And are there times when it should be absolutely avoided? “Its underlying message was unmistakable: Women should consider themselves first a vessel for human life and make decisions about their health and behavior based on that possibility,” Rebecca Ruiz wrote at Mashable, in a typical reaction. are unplanned–any woman who drinks alcohol should use birth control. First trimester exposure to nitrofurantoin was not associated with increased risk for total major congenital malformations or with specific malformations.Ĭongenital malformations nitrofurantoin pregnancy.Last year, the CDC ignited a firestorm of criticism by stating that women should “stop drinking alcohol if they are trying to get pregnant or could get pregnant”, and–because an estimated 50% of pregnancies in the U.S.
Exposure to nitrofurantoin was not associated with increased risk of major malformations in general (adjusted OR = 0.85, 95% CI 0.67-1.08) or with specific malformations. A total of 1,329 infants and abortuses had been exposed to nitrofurantoin during the first trimester of pregnancy. Our research included a total of 105,492 pregnancies, 1,112 of which involved pregnancy terminations for medical reasons. Associations between exposure to nitrofurantoin during the first trimester and major malformations were assessed.
A computerized database for medications dispensed to pregnant women in southern Israel was linked with records from the district hospital. To address these concerns, we conducted a large population-based retrospective cohort study to assess this possible association (including cases of medical terminations of pregnancy or stillbirth) and congenital malformations.
While medical literature generally defines nitrofurantoin as an antibiotic that is safe for use during the first trimester of pregnancy, new concerns about a possible association between congenital malformations following exposure to nitrofurantoin during the first trimester of pregnancy have recently surfaced. Antibacterial drugs are among the most common medications used by pregnant women.
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